THE ROLE OF THIOL GROUPS IN THE EXPRESSION OF THE ACTIVITY OF ARGINASE I AND II ISOENZYMES

There are some aspects of the proteins «self-organization» that not well studied, understanding relationship between conformational folding linked with formation a disulfide bond is important and challenging both from biophysical biochemical perspectives. Studies have attempted to elucidate role thiol groups in maintenance native conformation activity arginase I II different organ origin. It was identified depending on stage enzyme reactivation stability state formed oligomers, para-chloromercuribenzoate affects «self-organised» oligomers ways.